In the world of organic chemistry and industrial manufacturing, Phenylacetic Acid (CAS 103-82-2) stands out as a pivotal compound with diverse applications across multiple sectors. Known for its unique chemical structure and versatile properties, Phenylacetic Acid is a crucial raw material in the synthesis of pharmaceuticals, fragrances, and agrochemicals.
If you’re a chemist, a manufacturer, or an industry analyst seeking in-depth knowledge about Phenylacetic Acid, including its properties, uses, safety, and sourcing, this comprehensive guide is tailored for you. Drawing inspiration from leading chemical suppliers like BMK Oil, this article aims to provide detailed insights into Phenylacetic Acid, ensuring you have all the necessary information to understand its significance fully. Dibenzyl Ketone (1,3-Diphenylacetone)
What Is Phenylacetic Acid?
Phenylacetic Acid, with the chemical formula C₈H₈O₂, is an aromatic organic compound characterized by the presence of a phenyl group attached to an acetic acid moiety. Its CAS (Chemical Abstracts Service) registry number is 103-82-2.
Chemical Structure and Properties

- Molecular Formula: C₈H₈O₂
- Molecular Weight: 136.15 g/mol
- Appearance: Colorless crystalline solid or white powder
- Odor: Slightly sweet, honey-like aroma
- Melting Point: Approximately 76-78°C
- Boiling Point: Around 245°C
- Solubility: Slightly soluble in water; soluble in organic solvents such as ethanol, ether, and chloroform
Chemical Characteristics
Phenylacetic Acid exhibits typical aromatic carboxylic acid behavior. It can undergo various chemical reactions, including esterification, halogenation, and reduction, making it a versatile intermediate in chemical synthesis.
Industrial Applications of Phenylacetic Acid
Phenylacetic Acid’s unique chemical structure makes it a valuable precursor and intermediate in numerous industrial processes. Below are some of its primary applications:
1. Pharmaceutical Industry
Phenylacetic Acid is a key intermediate in the synthesis of various pharmaceutical compounds, including:
- Penicillin Derivatives: It serves as a precursor in the production of penicillin G and other β-lactam antibiotics.
- Antidepressants and Anxiolytics: Used in manufacturing certain drugs targeting neurological conditions.
- Hormones and Steroids: It acts as a building block in synthesizing steroid hormones.
2. Fragrance and Flavor Industry
Due to its slightly sweet aroma, Phenylacetic Acid is used in manufacturing perfumes, fragrances, and flavorings. Its scent profile resembles honey and floral notes, making it ideal for high-end cosmetic products.
3. Agrochemical Sector
Phenylacetic Acid is employed in synthesizing herbicides, pesticides, and plant growth regulators, contributing to sustainable agriculture practices.
4. Organic Synthesis and Research
In laboratory settings, Phenylacetic Acid serves as an important reagent in organic synthesis, enabling chemists to develop new compounds and study reaction mechanisms.
Sourcing and Supply of Phenylacetic Acid
Leading chemical suppliers like BMK Oil provide high-quality Phenylacetic Acid (CAS 103-82-2) to industries worldwide. Their products meet stringent quality standards, ensuring purity and consistency for various applications.
Quality and Purity Standards
- Purity Levels: Typically ≥ 99%
- Packaging: Available in drums, bottles, or bulk containers
- Compliance: Meets international safety and quality certifications
Why Choose BMK Oil?
BMK Oil is renowned for its reliable supply chain, competitive pricing, and expert customer service. They source Phenylacetic Acid from trusted manufacturers, ensuring compliance with global standards such as REACH, OSHA, and EPA.
Safety and Handling of Phenylacetic Acid
While Phenylacetic Acid is invaluable industrially, it is vital to handle it with care due to its chemical properties.
Safety Precautions
- Personal Protective Equipment (PPE): Gloves, goggles, lab coats
- Storage: Store in a cool, dry, well-ventilated area away from incompatible substances
- Handling: Avoid inhalation, ingestion, and skin contact
- First Aid Measures: Rinse affected areas with water; seek medical attention if exposure occurs
Environmental Impact
Proper disposal and containment measures are necessary to prevent environmental contamination. Phenylacetic Acid should be disposed of following local regulations and guidelines.
Environmental and Regulatory Considerations
The production and use of Phenylacetic Acid are subject to various environmental and safety regulations globally.
- REACH Compliance: Ensuring safe handling and registration in the European Union
- EPA Regulations: Managing emissions and waste disposal in the United States
- Global Standards: Adhering to international safety data sheet (SDS) requirements
Synthesis of Phenylacetic Acid
Phenylacetic Acid can be synthesized through several methods, including:
1. Hydrolysis of Phenylacetonitrile
Phenylacetonitrile undergoes acid hydrolysis to produce Phenylacetic Acid.
2. Finkelstein Reaction
Reaction of benzyl chloride with sodium acetate, followed by oxidation, yields Phenylacetic Acid.
3. Catalytic Hydroxylation
Using catalytic processes to hydroxylate styrene derivatives to produce Phenylacetic Acid.
Market Trends and Future Outlook
The global demand for Phenylacetic Acid continues to grow, driven by its applications in pharmaceuticals, fragrances, and agrochemicals. The industry is witnessing innovations in synthesis methods, improving yield, purity, and environmental footprint.
Key Market Drivers
- Rising pharmaceutical research and development
- Expansion of the fragrance and flavor sector
- Increasing focus on sustainable and green chemistry processes
Challenges
- Fluctuations in raw material prices
- Strict regulatory environment
- Need for eco-friendly manufacturing techniques
Conclusion
Phenylacetic Acid (CAS 103-82-2) remains a cornerstone chemical in multiple industries, owing to its versatile chemical structure and broad application spectrum. Whether in the production of life-saving antibiotics, delightful fragrances, or eco-friendly agrochemicals, its importance is undeniable.
For industries seeking reliable sources of high-quality Phenylacetic Acid, trusted suppliers like BMK Oil offer products that meet international standards, ensuring safety, purity, and consistent supply.
Final Note
If you’re interested in sourcing Phenylacetic Acid or learning more about its applications, quality standards, or safety protocols, contact reputable chemical suppliers today. Staying informed and compliant ensures the success of your projects and the safety of your operations.
