Description
6 apb for sale
6-APB (6-(2-aminopropyl)benzofuran), also known informally as “Benzo Fury,” is a synthetic entactogen and stimulant drug belonging to the benzofuran and phenethylamine families. It is structurally similar to MDA and MDMA, but differs in that the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring and acts as a serotonin-norepinephrine-dopamine releasing agent.
6-APB is also the unsaturated benzofuran derivative of 6-APDB. It may appear as a tan or brown grainy powder.
Effects and Experience
6-APB is reported to produce entactogenic, stimulant, and mild psychedelic effects in humans.
- Sensory changes: Enhanced appreciation for music, bright colors, and visual distortions or mild geometric patterns.
- Empathy and mood: Feelings of euphoria, emotional openness, sociability, and affection.
- Physical sensations: Heavy body load, waves of tingling euphoria, and sometimes physical sedation or “couch-lock” at higher amounts, contrasting with the purely energetic push of other amphetamines.
- Duration: Known for a slow onset and a significantly longer total duration compared to MDMA.
Pharmacodynamics
6-APB acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC Tooltip half-maximal effective concentration values for monoamine release of 36 nM for serotonin , 14 nM for norepinephrine, and 10 nM for dopamine in rat brain synaptosomes.
Simultaneously, 6-APB is a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), with affinities (Ki) of 117 nM for the norepinephrine transporter (NET), 150 nM for the dopamine transporter (DAT), and 2,698 nM for the serotonin transporter (SERT) as well as IC Tooltip half-maximal effective concentration values for monoamine reuptake inhibition of 930 nM for serotonin, 190 nM for norepinephrine, and 3,300 nM for dopamine.
Pharmacokinetics
The pharmacokinetics of 6 APB have not been studied, however, some information can be extracted from user reports. These suggest a slow onset of 40 to 120 minutes. The drugs peak effects last 7 hours, followed by a comedown phase of approximately 2 hours, and after effects for up to 24 hours.
Buy 6 apb
Chemistry
6-APB, also known as 6-(2-aminopropyl)benzofuran, is a phenethylamine, amphetamine, and benzofuran and an analogue of 3,4-methylenedioxyamphetamine (MDA).
Formula: C11H13NO
Molecular Formula: C11H13NO • HCl
CAS Number: 286834-85-3 | 286834-84-2
Purity: ≥98%
Molar mass: 175.231 g·mol−1
Formulation: A crystalline solid
Formula Weight: 211.7
Synonyms: 6-(2-Aminopropyl)Benzofuran, Benzo Fury
Duration of action: 6 – 9 hours
Other names: 6-(2-Aminopropyl)benzofuran
Class: Serotonin–norepinephrine–dopamine releasing agent; Serotonin 5-HT2 receptor agonist; Entactogen; Stimulant; Psychedelic
Formal name: α-methyl-6-benzofuranethanamine, monohydrochloride
Storage: -20°C
Shipping: Room temperature; may vary elsewhere
Synthesis
The chemical synthesis of 6-APB has been described. The synthesis by Briner and colleagues entailed refluxing 3-bromophenol with bromoacetaldehyde diethylacetal and sodium hydride to give
the diethyl acetal, which then was heated with polyphosphoric acid to give a mixture of bromobenzofuran structural isomers: 4-bromo-1-benzofuran and 6-bromo-1-benzofuran.
The isomers were separated by silica gel column chromatography, then converted to their respective propanone derivatives, and then reductively aminated to give 6-APB and 4-APB, both of which were converted to their HCl ion pairs for further examination.
Reviews
There are no reviews yet.